Apoptosis Antibodies

Apoptosis is the process by which cells die a programmed death or PCD. The process is facilitated by processes within the cell using certain biochemicals that lead to changes in cell morphology and eventually leads to the cell dying. This is a natural process in the cell cycle and is necessary to maintain proper alignments of organ and organelle structure. Defects in the apoptosis of cells can lead to diseases such as cancer. Each cell must die in order to make room for fresh replacements. Apoptosis can also be useful in the breakdown of cells into their parts for recycling and re-use. It is essentially induction of cell suicide. Apoptosis can be triggered by internal or external signals. Some of the identifying events of apoptosis include DNA fragmentation, shrinkage, and releasing of energy stores. Apoptosis antibodies are involved in apoptosis and can facilitate, block, or slow down the process of pre-programmed cell death.

Anti-Fas Ligand antibody is a cytokine that binds to a receptor that communicates the apoptotic signal into cells. This can halt the message and postpone T-cell mediated apoptosis. Defects in this antibody result in autoimmune syndromes like autoimmune lymphoproliferative syndrome type 1B. Lymphoproliferative disorders are a family of conditions characterized by excessive lymphocyte production. Lymphoproliferative syndrome type 1B, also known as Canale-Smith Syndrome, is a childhood disorder involving hemolytic anemia, enlarged lymph nodes and spleen, and low platelet counts. The anti-hemopexin antibody binds to heme in blood and transports it to the liver for it to be broken down. After which, the iron is recovered and used in other applications and the free hemopexin is returned into general circulation to start the process over again.

Apoptosis Antibodies

Product Number Title Tested Applications Host Species Clonality
AC11-0102 Anti-Cullin 2 Antibody ELISA Goat Polyclonal
AC11-0119 Anti-iASPP Antibody ELISA Goat Polyclonal
AC11-0151 Anti-ILP2 Antibody ELISA Goat Polyclonal
AC11-0153 Anti-BIRC6 Antibody ELISA Goat Polyclonal
AC11-0154 Anti-Bik Antibody ELISA Goat Polyclonal
AC11-0155 Anti-Bik Antibody ELISA Goat Polyclonal
AC11-0156 Anti-Bcl2A1 Antibody ELISA Goat Polyclonal
AC11-0157 Anti-Bcl G Antibody ELISA Goat Polyclonal
AC11-0158 Anti-Bmf Antibody ELISA Goat Polyclonal
AC11-0159 Anti-PUMA Antibody ELISA Goat Polyclonal
AC11-0175 Anti-PNPT1 Antibody ELISA Goat Polyclonal
AC11-0202 Anti-CYFIP2 Antibody ELISA Goat Polyclonal
AC11-0203 Anti-CYFIP2 Antibody ELISA Goat Polyclonal
AC11-0217 Anti-NOX5 Antibody ELISA Goat Polyclonal
AC11-0259 Anti-BLK Antibody ELISA Goat Polyclonal
AC11-0260 Anti-BLK Antibody ELISA Goat Polyclonal
AC11-0272 Anti-p63 Antibody ELISA Goat Polyclonal
AC11-0297 Anti-SON Antibody ELISA Goat Polyclonal
AC11-0298 Anti-SIRT1 Antibody ELISA Goat Polyclonal
AC11-0312 Anti-MDMX Antibody ELISA Goat Polyclonal