Anti-CD22 Antibody (Pacific Blue™)

$315.00
Product Number: PB-506

Anti-CD22 monoclonal antibody raised in mouse, conjugated to Pacific Blue™.

Antibody Information
Host Species: 
Mouse
Clonality: 
Monoclonal (IS7)
Clone: 
IS7
Isotype: 
IgG1
Conjugate: 
Pacific Blue™
Immunogen Type: 
Anti-CD22 antibody (Pacific Blue™) was raised against Reh human cell line.
Species Reactivity: 
Human
Specificity: 

Anti-CD22 antibody (Pacific Blue™) reacts with CD22 (BL-CAM), a 130 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed in the cytoplasm of pro-B and pre-B lymphocytes, and on the surface of mature and activated B lymphocytes; it is lost on plasma cells, peripheral blood T lymphocytes, granulocytes and monocytes.

HLDA Workshop Code(s): 
HLDA IV; WS Code B 227<br /><br />HLDA V; WS Code B CD22.8
Product Information
Amount: 
100 tests
Buffer: 
Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free bovine serum albumin (BSA) as a stabilizing agent.
Storage: 
Store antibody in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Short-term exposure to room temperature should not affect the quality of the antibody. However, if reagent is stored under any conditions other than those specified, the conditionsmust be verified by the user.
Application Details
Tested Applications: 
FC
Application Overview: 
Anti-CD22 antibody (Pacific Blue™) can be used for flow cytometry.
Additional Information
Alternative Names: 
CD22, BL-CAM
Product Citation(s): 

Leukocyte Typing V., Schlossman S. et al. (Eds.), Oxford University Press (1995).

Leukocyte Typing IV., Knapp W. et al. (Eds.), Oxford University Press (1989).

Background Publication(s): 

Tedder TF, Poe JC, Haas KM: CD22: A Multifunctional Receptor That Regulates B Lymphocyte Survival and Signal Transduction. Adv Immunol. 2005;88:1-50.

Tateno H, Li H, Schur MJ, Bovin N, Crocker PR, Wakarchuk WW, Paulson JC: Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity. Mol Cell Biol. 2007 Aug;27(16):5699-710.

Walker JA, Smith KG: CD22: an inhibitory enigma. Immunology. 2007 Dec 7

Supplier Informaiton
Supplier: 
EXBIO
Supplier Product Number: 
PB-506-T100
Supplier Product Name: 
Mouse monoclonal antibody to CD22 / BL-CAM
Antibodies
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Monoclonal Antibodies
Antibodies by Clonality
Conjugated Antibodies
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(FC) Flow Cytometry Antibodies
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Pacific Blue™ Antibodies
EXBIO

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